When his small hamlet of Birzirkenstadt is ravaged by a deadly plague, the young and rebellious Doctor Janick reveals a radical cure. But his revolutionary theories about life and death label him a heretic and he is rewarded with banishment. As Janick disappears into the wild with his secret love, Esmeralda succumbs to the deadly disease and the superstitious doctors are helpless to cure her. Enter a mysterious masked figure known only as the Creator who snatches Esmeralda's body from its grave and begins to conduct weird experiments…their objective: to bring her back from death's cold embrace.